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What is Regenerative Medicine? Regenerative medicine is the sub-branch of medicine aimed at regenerating tissues and promoting new blood flow with the use of non-autologous and autologous substances.
What Conditions can be treated with Regenerative Medicine?
Regenerative medicine can be used to treat a variety of conditions. Low back or thoracic mid-back pain including degenerative disc disease and sacro-iliac joint instability/dysfunction, neck pain, neck torticolis, knee pain, knee meniscal tears, wrist or hand pain, osteoarthritis, shoulder pain including rotator cuff tears, elbow pain including golfers or tennis elbow, foot pain including plantar fasciitis, ankle pain or instability, hypermobility, osteitis pubis, IT band syndrome, piriformis syndrome to name a few of the conditions treated.
What is Prolotherapy?
Prolotherapy is a way of promoting tissue regeneration by recruiting the body’s own healing mechanisms to stimulate an inflammatory reaction and the subsequent healing cascade to regrow new tissue in a weakened or injured area. The process is also know as Non-Surgical Ligament and Tendon Reconstruction and Regenerative Joint Injection. Prolotherapy or proliferation therapy or regenerative injection therapy is an alternative medicine treatment of tissue with the injection of an irritant solution such as dextrose solution into a joint space, weakened ligament, or tendon insertion to relieve pain and regenerate the tissues.
After each treatment of prolotherapy, the body is tricked to begin the healing process again and regrow new tendon or tissue into the area. Treatment is done with local anesthetic so that it is not painful.
What is PRP?
PRP (platelet-rich plasma) is a volume of autologous plasma with the platelet concentration above baseline. PRP has been clinically applied for its healing properties, and now is widely applied in many therapeutic areas such as disc problems, joint pain, knee pain, hip pain. Platelets can secrete a variety of growth factors, including PDGF, IGF-1, TGF-β, VEGF, bFGF, EGF, and CTGF*, among others. All these growth factors play significant roles in promoting the proliferation of tissues and angiogenesis. Platelets also contain antibacterial and bactericidal proteins that may influence the process of inflammatory responses by inducing the synthesis of some molecules, such as integrins, interleukins and chemokines. Last but not least, platelets may serve as a biological sponge because they can absorb, store and transfer some small molecules that regulate tissue regeneration. PRP represents a new biotechnology in tissue engineering and has become a popular clinical treatment for various tissue healing applications without any immune rejections.
- PDGF: Platelet Derived Growth Factor, IGF-1: Insuliin-Like Growth Factor-1,TGF-β: Transforming Growth Factor Beta-1, VEGF: Vascular Endothelial Growth Factor,bFGF: Basic-fibroblastic Growth Factor,EGF: Epidermal Growth Factor,CTGF: Connective Tissue Growth Factor
How can you obtain PRP? PRP is obtained by taking a volume of blood and concentrating the platelets with the use of a centrifuge. The platelet-rich plasma layer is then extracted from the red blood cells. These platelets can then be injected into the tissues of interest.
At CSS, regenerative medicine and PRP are used to help with knee pain, tennis elbow, chronic shoulder pain, chronic greater trochanter bursitis, trigger points, and discogenic back pain.
Patient’s with chronic back and neck pain should consider regenerative medicine techniques like Prolotherapy or PRP to help with their painful conditions.
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